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New Treatments For Vitiligo

New Treatments For VitiligoVitiligo is a disease that causes the loss of skin color in blotches. The extent and rate of color loss from vitiligo is unpredictable. It can affect the skin on any part of your body. It may also affect hair, the inside of the mouth and even the eyes.

Normally, the color of hair, skin and eyes is determined by melanin. Vitiligo occurs when the cells that produce melanin die or stop functioning.

Vitiligo affects people of all skin types, but it may be more noticeable in people with darker skin. It can be stressful or make you feel bad about yourself. Treatment for vitiligo may improve the appearance of the affected skin but does not cure the disease。

there are many treatments available for vitiligo, and the type of treatment should be tailored for each patient, according to his or her needs. Most treatments are prescribed “off label”, since they are not FDA-approved for vitiligo, yet are approved for other skin diseases.

Vitiligo New Treatment Options

When it comes to the new treatments for Vitiligo,there are four mainly options are currently available for the treatment of vitiligo:

Topical steroids: Topical steroids are widely available and have been used for many years to treat vitiligo. They are cheap and effective, however they have some side effects, including thinning of the skin, stretch marks, and others. When used correctly, these can be largely avoided.

Topical tacrolimus: Topical tacrolimus is a relatively new treatment for vitiligo that has similar efficacy as topical steroids and few side effects that include a mild burning sensation after application and brief flushing of the skin after alcohol consumption. This is currently an expensive treatment that is not always covered by insurance.

nbUVB (Narrow-band ultraviolet light B): nbUVB is currently the most successful treatment for patients with vitiligo. It is largely safe when administered correctly, but requires a time commitment as it is most often performed in a dermatologist’s office 2-3x per week. The way that nbUVB is administered is very important for safety and treatment success, as too much light could burn your skin, and too little light may not improve your vitiligo. Unlike PUVA treatment (below), nbUVB does not appear to increase the risk for skin cancer.

PUVA (Psoralen plus Ultraviolet light A): PUVA combines the chemical psoralen with UVA exposure, which can come from the sun or a light booth in a dermatology clinic; many countries offer topicals that contain PUVA and tell the patient to sit in the sun after applying it. While this method was initially used for vitiligo and can be effective, it is not any better than nbUVB (above) but has many side effects, including skin cancer risk and dark spots returning that don’t match the normal skin color. It is for these reasons PUVA is not widely used for vitiligo anymore.

Monobenzone: Monobenzone is the only FDA-approved treatment for vitiligo, however its purpose is to worsen the disease and remove the remaining pigment on your body in order to make the skin color more even. This is only recommended for those patients with widespread disease that have failed other options to return the pigment to the skin. It is not widely available, and must be produced by a compounding pharmacy.

Others: Many other treatments have been discovered for vitiligo, but it have either no proven efficacy in disease, or have such little efficacy that we prioritize other proven treatments instead.


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