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Why Psoriasis Will Occur the Desquamation Symptom

 Desquamation Symptom, PsoriasisThe serious desquamation symptom of psoriasis is related to pathology features.

The normal epidermal include basal layer, spinous layer, granular layer, transparent layer, and stratum corneum five layers. The stratum corneum is the outermost layer of the cells, the epidermis which our eyes can see. The keratinocytes are the major cells of epidermis, which is formed from the basal layer which convert to the stratum corneum gradually.The movement time, the basal layer converts to the stratum corneum, is called the epidermis cross time. Every day, the keratinocytes move into the stratum corneum slowly, and in the process they become mature and aging,finally forming desquamation which shed from the skin. But because the process is very slow, and the exfoliated cells are very little, so the desquamation is not easy to be perceived by us.

When patients get psoriasis, the epidermis keratinocytes are affected by many factors, so the proliferation speed is greatly accelerated, the time of mitosis is shortened to 7.5 days ( the normal time is 457 hours), the epidermal through time has also been shortened to 3-7 days (the normal time is 28 days), which causes the not mature keratinocytes are quickly moved to the cuticle, so there are a lot of accumulations, forming mica-like scales. It is different from the normal skin cuticle, this immature cuticle arrangement is very loose and grow rapidly, when you gently scrape or rub, a large number of silver scaling will fall from the skin surface. If the skin is dry in usual time or in winter, the patients’ desquamationit condition will become more severe.

The external symptoms are similar for every psoriasis patient, actually there are many kinds and the therapies vary from people to people. If you want a further knowledge, you can consult the online doctor.


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